This was announced by researchers that have been working on this compound, from the aminopyridine class, for several years. Unlike conventional multidrug malaria treatments that the malaria parasite has become resistant to, Professor Kelly Chibale and his colleagues now believe that they have discovered a drug that over 18 months of trials ”killed these resistant parasites instantly”.
Animal tests also showed that it was not only safe and effective, but there were no adverse reported side effects. Clinical tests are scheduled for the end of 2013.
Potential Impact for Africa
If this tablet is approved in coming years, this achievement will surely usher in a new age for science in Africa. It will save millions upon millions of lives on the continent, helping avoid at least 24 percent of child deaths in sub-Saharan Africa. Professor Chibale proudly explains: “This is the first ever clinical molecule that’s been discovered out of Africa, by Africans, from a modern pharmaceutical industry drug discovery programme. The potent drug has been tested on animals and has shown that a single oral dose has completely cured those infected with malaria parasites.”
This “super pill” could potentially cure millions of people every year, and save the lives of over one million people from around the world each year. This “cure” will most likely save health care systems throughout the developing world billions of dollars and open new areas for development and settlement.
If this proves to be true, it'll be huge and wonderful news.
About 3.3 billion people – half of the world's population – are at risk of malaria. In 2010, there were about 216 million malaria cases (with an uncertainty range of 149 million to 274 million) and an estimated 655 000 malaria deaths (with an uncertainty range of 537 000 to 907 000). Increased prevention and control measures have led to a reduction in malaria mortality rates by more than 25% globally since 2000 and by 33% in the WHO African Region.
People living in the poorest countries are the most vulnerable to malaria. In 2010, 90% of all malaria deaths occurred in the WHO African Region, mostly among children under five years of age.
Lord, let this be true.
H/T to CMR.